Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26069604 | 0.72 | KDM4E (0.31) | KDM4ELMNACYP2C19 | |
| SCHEMBL26069605 | 0.70 | — | — | |
| SCHEMBL24162634 | 0.69 | — | — | |
| SCHEMBL24355393 | 0.68 | — | — | |
| SCHEMBL1270488 | 0.67 | — | — | |
| SCHEMBL12550457 | 0.67 | — | — | |
| SCHEMBL15114498 | 0.67 | KDM4E (0.41) | KDM4ELMNACYP2C19 | |
| SCHEMBL17813310 | 0.65 | — | — | |
| SCHEMBL272618 | 0.64 | — | — | |
| SCHEMBL20275584 | 0.63 | KDM4E (0.32) | KDM4ELMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2022083657-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-04-28 | — | — | WO | disclosed |