Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 2/20 | 0.65 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.65 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.65 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 13/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.59 |
| ▸ | NPC1 | O15118 | 11/20 | 0.59 |
| ▸ | RAB9A | P51151 | 10/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745786 | 1.00 | KCNN1 (0.65) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL24357989 | 0.87 | KCNN1 (0.73) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL30745744 | 0.83 | MEN1 (0.72) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL27039690 | 0.83 | MEN1 (0.72) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL24357955 | 0.81 | KCNN1 (0.65) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL24358162 | 0.81 | KCNN1 (0.65) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL5173768 | 0.81 | KCNN1 (0.80) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL29601174 | 0.81 | KCNN1 (0.80) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL24358169 | 0.81 | MEN1 (0.74) | KCNN1KCNN2KCNN3SLC2A1MEN1 | |
| SCHEMBL24358035 | 0.81 | KCNN1 (0.64) | KCNN1KCNN2KCNN3SLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION | 2024-01-25 | — | — | US | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240025891-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CYP8B1, PAH, INHA | KCNN1 4605/4885KCNN2 4592/4885KCNN3 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.