Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 18/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435918 | 0.93 | PTGER4 (0.49) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL2930321 | 0.89 | PTGER4 (0.57) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL14307440 | 0.89 | PTGER4 (0.57) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL2937605 | 0.89 | PTGER4 (0.57) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL2429101 | 0.88 | PTGER4 (0.43) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL2428028 | 0.85 | PTGER4 (0.50) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL12289221 | 0.85 | PTGER4 (0.50) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL12289269 | 0.83 | PTGER4 (0.47) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL12289272 | 0.83 | PTGER4 (0.47) | PTGER4CYP1A2CYP2D6 | |
| SCHEMBL4196361 | 0.83 | PTGER4 (0.39) | PTGER4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026270-B2 | Benzo [F] isoindoles as EP4 receptor agonists | GLAXO GROUP LIMITED (GB) | 2011-09-27 | — | — | US | disclosed |