SCHEMBL2435958

SCHEMBL2435958

C[C@@H]1N[C@@H](CO)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FUCA1 P04066 8/20 1.00
▸ FUCA2 Q9BTY2 1/20 0.95
▸ GLA P06280 3/20 0.65
▸ AGL P35573 2/20 0.65
▸ GAA P10253 2/20 0.65
▸ GBA2 Q9HCG7 1/20 0.65
▸ GBA1 P04062 1/20 0.65
▸ MGAM O43451 5/20 0.62
▸ GANC Q8TET4 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14268491 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL9912298 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL3443029 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL1650553 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL17178434 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL15593238 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL9343563 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL17178435 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL2437315 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA
SCHEMBL1680180 1.00 FUCA1 (1.00) FUCA1FUCA2GLAAGLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110237538-A1 TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES SUMMIT CORPORATION PLC (GB) 2011-09-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237538-A1 TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES GAA, MAN2B1, GBA1 FUCA1 17/4885FUCA2 18/4885GLA 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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