Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | ELANE | P08246 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | CTSG | P08311 | 1/20 | 0.59 |
| ▸ | CMA1 | P23946 | 1/20 | 0.59 |
| ▸ | CTRC | Q99895 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | EP300 | Q09472 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990677 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL1503988 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL14189454 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL2435698 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL8714088 | 1.00 | MEN1 (1.00) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL7825065 | 0.83 | MEN1 (0.70) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL16775234 | 0.83 | KMT2A (0.70) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL16759895 | 0.83 | KMT2A (0.70) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL22647700 | 0.81 | KMT2A (0.68) | MEN1KMT2AALDH1A1ELANEF2 | |
| SCHEMBL22571107 | 0.81 | KMT2A (0.66) | MEN1KMT2AALDH1A1ELANEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |