SCHEMBL24360491

SCHEMBL24360491

O=C1CCC(I)(C(=O)O)CN1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24360493 0.74 POLB (0.46) CRBN
SCHEMBL19797973 0.72 FFAR3 (0.44) CRBN
SCHEMBL16323338 0.69
SCHEMBL18766523 0.66 CRBN (0.39) CRBN
SCHEMBL7091308 0.64
SCHEMBL9210113 0.64 CRBN (0.38) CRBN
SCHEMBL24884910 0.63 SMN1; SMN2 (0.35) CRBN
SCHEMBL470499 0.63
SCHEMBL249184 0.63
SCHEMBL10920234 0.63 CRBN (0.42) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3258929-B1 FACTOR IXA INHIBITORS MERCK SHARP & DOHME (US) 2022-04-27 EP disclosed