Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | FABP2 | P12104 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599968 | 0.91 | HPGD (0.64) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL11571590 | 0.86 | PPARA (0.74) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL11509940 | 0.81 | KMT2A (0.60) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL275229 | 0.80 | POLB (0.80) | ALDH1A1POLBKMT2A | |
| SCHEMBL2440421 | 0.80 | PPARA (0.66) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL14290327 | 0.80 | PPARA (0.55) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL11571923 | 0.79 | PPARA (0.71) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL2558984 | 0.79 | PPARA (0.71) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL11540738 | 0.78 | POLB (0.56) | ALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL5482435 | 0.78 | PPARA (0.59) | PPARAPPARGALDH1A1FABP2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |