Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24364795 | 0.81 | ESR2 (0.33) | ESR2 | |
| SCHEMBL25322649 | 0.79 | HRH3 (0.41) | — | |
| SCHEMBL25322631 | 0.79 | KCNH2 (0.54) | KCNH2PTGS2 | |
| SCHEMBL25322627 | 0.79 | KCNH2 (0.54) | KCNH2PTGS2 | |
| SCHEMBL31145247 | 0.78 | ESR2 (0.53) | ESR2 | |
| SCHEMBL29324808 | 0.78 | ESR2 (0.53) | ESR2 | |
| SCHEMBL24364303 | 0.78 | ESR2 (0.53) | ESR2 | |
| SCHEMBL25321512 | 0.76 | MAPT (0.39) | ESR2 | |
| SCHEMBL24233794 | 0.76 | MAPT (0.39) | ESR2 | |
| SCHEMBL14963942 | 0.76 | MAPT (0.39) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127256-A1 | COMPOUNDS AND METHODS OF USE | F12, C1R, ABCG2 | KCNH2 1114/4885REN 19/4885ESR2 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.