Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439673 | 0.93 | HTT (0.49) | MAPTMAP2K1USP2HTTRECQL | |
| SCHEMBL1228956 | 0.93 | MAPT (0.50) | MAPTMAP2K1USP2HTTRECQL | |
| SCHEMBL5941017 | 0.92 | HTT (0.48) | MAPTMAP2K1USP2HTTRECQL | |
| SCHEMBL2436615 | 0.80 | MAP2K1 (0.51) | MAPTMAP2K1USP2HTTRECQL | |
| SCHEMBL5941039 | 0.79 | HTT (0.49) | MAPTMAP2K1USP2HTTRECQL | |
| SCHEMBL21917164 | 0.79 | HTT (0.56) | MAPTHTTRECQLALDH1A1LMNA | |
| SCHEMBL5941099 | 0.79 | HTT (0.64) | MAPTMAP2K1HTTRECQLALDH1A1 | |
| SCHEMBL2440881 | 0.79 | HTT (0.49) | MAPTMAP2K1USP2HTTRECQL | |
| SCHEMBL3527060 | 0.79 | HTT (0.68) | MAPTMAP2K1HTTRECQLALDH1A1 | |
| SCHEMBL21917354 | 0.78 | HTT (0.43) | MAPTMAP2K1USP2HTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362909-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010039778-A2 | MAMMALIAN GENES INVOLVED IN INFECTION | Zirus, Inc. (US) | 2010-04-08 | — | — | WO | disclosed |