Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319090 | 0.92 | MAOB (0.40) | SMN1; SMN2ALDH1A1F10SPHK2GAA | |
| SCHEMBL30587015 | 0.91 | F10 (0.42) | SMN1; SMN2ALDH1A1F10SPHK2GAA | |
| SCHEMBL21546126 | 0.91 | F10 (0.42) | SMN1; SMN2ALDH1A1F10SPHK2GAA | |
| SCHEMBL13634584 | 0.91 | F10 (0.42) | SMN1; SMN2ALDH1A1F10SPHK2GAA | |
| SCHEMBL13525981 | 0.89 | F10 (0.38) | ALDH1A1F10SPHK2GAAMAPT | |
| SCHEMBL26167876 | 0.89 | LOX (0.43) | SMN1; SMN2ALDH1A1F10SPHK2GAA | |
| SCHEMBL24346423 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1F10SPHK2GAA | |
| SCHEMBL23346373 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1F10GAAMAPT | |
| SCHEMBL24199561 | 0.86 | F10 (0.40) | ALDH1A1F10SPHK2GAAMAPT | |
| SCHEMBL14611467 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022083686-A1 | MODIFIED NUCLEOSIDE OR NUCLEOTIDE | 深圳华大生命科学研究院 | 2022-04-28 | — | — | WO | disclosed |