SCHEMBL24371566

SCHEMBL24371566

C[C@]1(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O[C@@H](n2ccc(=S)[nH]c2=O)[C@@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 10/20 0.59
P2RY2 P41231 16/20 0.59
P2RY4 P51582 12/20 0.59
P2RY14 Q15391 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14929167 0.90 P2RY6 (0.72) P2RY6P2RY2P2RY4
SCHEMBL18573814 0.90 P2RY6 (0.72) P2RY6P2RY2P2RY4
SCHEMBL18573813 0.90 P2RY6 (0.72) P2RY6P2RY2P2RY4
SCHEMBL14946274 0.90 P2RY6 (0.72) P2RY6P2RY2P2RY4
SCHEMBL23898181 0.87 P2RY2 (0.59) P2RY6P2RY2P2RY4P2RY14
SCHEMBL17976685 0.86 P2RY2 (0.58) P2RY6P2RY2P2RY4P2RY14
SCHEMBL23897567 0.85 P2RY6 (0.56) P2RY6P2RY2P2RY4P2RY14
SCHEMBL17976682 0.84 P2RY2 (0.56) P2RY6P2RY2P2RY4P2RY14
SCHEMBL17971932 0.84 P2RY2 (0.56) P2RY6P2RY2P2RY4P2RY14
SCHEMBL21418446 0.84 P2RY2 (0.55) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3043803-B1 NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES UNIV EMORY (US) 2022-04-27 EP disclosed