Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.48 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812469 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL19812468 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL19812452 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL19812457 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL10962117 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL28816729 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL19812478 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL4826887 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| SCHEMBL9004304 | 0.97 | EPHX1 (0.52) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Hydrochloric Acid SCHEMBL27725444 | 0.94 | EPHX1 (0.50) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032786-A | Oil-in-water emulsion composition, method for producing same, and use thereof | 陶氏东丽株式会社 | 2020-04-17 | — | — | CN | disclosed |
| US-8012901-B1 | Method of synthesizing enantiopure mexiletine analogues and novel β-thiophenoxy and pyridyl ethers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-06 | — | — | US | disclosed |
| WO-2004035614-A1 | SYNTHETIC OR PARTIALLY PURIFIED PEPTIDES WHICH CAN BIND TO SPECIFIC SUBUNITS OF G PROTEINS AND USES THEREOF | KARO BIO AB (SE) | 2004-04-29 | — | — | WO | disclosed |
| EP-1073891-A2 | METHOD OF PREDICITING RECEPTOR MODULATING ACTIVITY | Karo Bio USA, Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| EP-1002235-A1 | METHOD OF IDENTIFYING AND DEVELOPING DRUG LEADS | Novalon Pharmaceutical Corporation (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999054728-A2 | METHOD OF PREDICTING RECEPTOR MODULATING ACTIVITY | KARO BIO USA, INC. (US) | 1999-10-28 | — | — | WO | disclosed |
| EP-0937253-A1 | IDENTIFICATION OF DRUGS USING COMPLEMENTARY COMBINATORIAL LIBRARIES | Novalon Pharmaceutical Corporation (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1999006839-A1 | METHOD OF IDENTIFYING AND DEVELOPING DRUG LEADS | NOVALON PHARMACEUTICAL CORPORATION (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1998019162-A9 | IDENTIFICATION OF DRUGS USING COMPLEMENTARY COMBINATORIAL LIBRARIES | — | 1998-07-09 | — | — | WO | disclosed |
| WO-1998019162-A1 | IDENTIFICATION OF DRUGS USING COMPLEMENTARY COMBINATORIAL LIBRARIES | NOVALON PHARMACEUTICAL CORPORATION (US) | 1998-05-07 | — | — | WO | disclosed |