SCHEMBL24371783

SCHEMBL24371783

COC(CO)C(O)C(O)n1ccc(=S)[nH]c1=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 2/20 0.31
P2RY2 P41231 1/20 0.31
P2RY4 P51582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19171451 0.86 POLB (0.40) P2RY6P2RY2P2RY4
SCHEMBL13181850 0.86 POLB (0.40) P2RY6P2RY2P2RY4
SCHEMBL24371972 0.82 P2RY14 (0.32)
SCHEMBL19049916 0.76 POLB (0.40) P2RY6P2RY2P2RY4
SCHEMBL19171320 0.75 POLB (0.39) P2RY6P2RY2P2RY4
SCHEMBL15691499 0.75 POLB (0.39) P2RY6P2RY2P2RY4
SCHEMBL23559388 0.74 SMN1; SMN2 (0.45)
SCHEMBL19170853 0.74 POLB (0.38) P2RY6P2RY2P2RY4
SCHEMBL15691460 0.74 POLB (0.38) P2RY6P2RY2P2RY4
SCHEMBL24371356 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3043803-B1 NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES UNIV EMORY (US) 2022-04-27 EP disclosed