SCHEMBL24371787

SCHEMBL24371787

COC(COP(=O)(NC(C)C(=O)OC(C)C)Oc1ccccc1)[C@H](O)C(C)(O)n1ccc(=O)[nH]c1=S

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
BTN3A1 O00481 9/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16566276 0.86 CYP3A4 (0.55) CYP3A4CYP2C9BTN3A1
SCHEMBL24371965 0.84 CYP3A4 (0.50) CYP3A4CYP2C9BTN3A1
SCHEMBL15739616 0.84 CYP3A4 (0.51) CYP3A4CYP2C9BTN3A1
SCHEMBL18430139 0.83 CYP3A4 (0.50) CYP3A4CYP2C9BTN3A1
SCHEMBL24371399 0.81 CYP3A4 (0.33) CYP3A4CYP2C9
SCHEMBL21418701 0.80 CYP3A4 (0.51) CYP3A4CYP2C9BTN3A1
SCHEMBL24371371 0.79 P2RY14 (0.34)
SCHEMBL24371799 0.79 P2RY14 (0.34)
SCHEMBL19352534 0.79 BTN3A1 (0.50) CYP3A4CYP2C9BTN3A1
SCHEMBL16575783 0.79 CYP3A4 (0.49) CYP3A4CYP2C9BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3043803-B1 NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES UNIV EMORY (US) 2022-04-27 EP disclosed