Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 19/20 | 0.51 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057679 | 0.95 | IRAK4 (0.48) | IRAK4ILK | |
| SCHEMBL12058284 | 0.89 | IRAK4 (0.47) | IRAK4ILK | |
| SCHEMBL12057762 | 0.87 | IRAK4 (0.51) | IRAK4ILK | |
| SCHEMBL12057773 | 0.87 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL12058041 | 0.86 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL12058094 | 0.86 | IRAK4 (0.55) | IRAK4ILK | |
| SCHEMBL12057835 | 0.86 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL12058205 | 0.85 | IRAK4 (0.47) | IRAK4ILK | |
| SCHEMBL12037782 | 0.84 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL12058486 | 0.84 | IRAK4 (0.58) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192586-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2022087216-A1 | DOUBLE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |