Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 1.00 |
| ▸ | GBA1 | P04062 | 6/20 | 0.78 |
| ▸ | GUSB | P08236 | 2/20 | 0.77 |
| ▸ | GBA2 | Q9HCG7 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | UGCG | Q16739 | 3/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.52 |
| ▸ | SI | P14410 | 2/20 | 0.52 |
| ▸ | AGL | P35573 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435889 | 1.00 | GLB1 (1.00) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL3378984 | 1.00 | GLB1 (1.00) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL2435892 | 1.00 | GLB1 (1.00) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL2435887 | 1.00 | GLB1 (1.00) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL3234285 | 0.95 | GLB1 (0.91) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL18191086 | 0.93 | GUSB (0.88) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL15599061 | 0.93 | GUSB (0.88) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL2435897 | 0.91 | GUSB (0.92) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL2430986 | 0.91 | GUSB (0.92) | GLB1GBA1GUSBGBA2GAA | |
| SCHEMBL3378221 | 0.91 | GUSB (0.92) | GLB1GBA1GUSBGBA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237538-A1 | TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES | SUMMIT CORPORATION PLC (GB) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237538-A1 | TREATMENT OF LYSOSOMAL STORAGE DISORDERS AND OTHER PROTEOSTATIC DISEASES | GAA, MAN2B1, GBA1 | GLB1 33/4885GBA1 3/4885GUSB 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.