⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23993480 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL30224403 | 0.84 | — | — | |
| SCHEMBL30224738 | 0.82 | — | — | |
| SCHEMBL2068386 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL31400371 | 0.80 | — | — | |
| SCHEMBL24387898 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL31400329 | 0.80 | — | — | |
| SCHEMBL18894340 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL519207 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL18865027 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684305-B | Preparation method of 8, 8-difluoro-2, 6-diazaspiro [3.4] octane compound | 上海药坦药物研究开发有限公司 | 2025-11-28 | — | — | CN | disclosed |
| CN-119684305-B | Preparation method of 8, 8-difluoro-2, 6-diazaspiro [3.4] octane compound | 上海药坦药物研究开发有限公司 | 2025-11-28 | — | — | CN | disclosed |
| CN-119684305-A | Preparation method of 8, 8-difluoro-2, 6-diazaspiro [3.4] octane compound | 上海药坦药物研究开发有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119684305-A | Preparation method of 8, 8-difluoro-2, 6-diazaspiro [3.4] octane compound | 上海药坦药物研究开发有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119684305-A | Preparation method of 8, 8-difluoro-2, 6-diazaspiro [3.4] octane compound | 上海药坦药物研究开发有限公司 | 2025-03-25 | — | — | CN | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2022093856-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |