Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 16/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924929 | 0.83 | MME (1.00) | MME | |
| SCHEMBL5924982 | 0.83 | MME (1.00) | MME | |
| SCHEMBL5924746 | 0.83 | MME (1.00) | MME | |
| SCHEMBL7449382 | 0.78 | MME (0.74) | MMENPC1RAB9A | |
| SCHEMBL7449384 | 0.75 | MME (0.85) | MME | |
| SCHEMBL6940693 | 0.74 | MME (0.73) | MMEHSD17B10ATM | |
| SCHEMBL6940695 | 0.74 | MME (0.73) | MMEHSD17B10ATM | |
| SCHEMBL7446213 | 0.72 | MME (0.79) | MME | |
| SCHEMBL7446151 | 0.72 | MME (1.00) | MME | |
| SCHEMBL7449394 | 0.69 | MME (0.60) | MMENPC1RAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280729-B1 | CD20 THERAPIES, CD22 THERAPIES, AND COMBINATION THERAPIES WITH A CD19 CHIMERIC ANTIGEN RECEPTOR (CAR) - EXPRESSING CELL | NOVARTIS AG (CH) | 2022-04-27 | — | — | EP | disclosed |