Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348534 | 0.81 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL2269175 | 0.77 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL8349276 | 0.72 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL4574251 | 0.71 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL6269870 | 0.69 | KMT2A (0.55) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL12933403 | 0.69 | KMT2A (0.50) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL9350553 | 0.69 | KMT2A (0.68) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL6644838 | 0.69 | KMT2A (0.57) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL6640610 | 0.69 | KMT2A (0.57) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL5100534 | 0.69 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642199-B1 | BENZOFURANS AS IRAK4 MODULATORS | HOFFMANN LA ROCHE (CH) | 2022-04-27 | — | — | EP | disclosed |