Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 4/20 | 0.80 |
| ▸ | MLLT3 | P42568 | 3/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29622146 | 1.00 | MLLT1 (0.80) | MLLT1MLLT3TSHRALDH1A1LMNA | |
| SCHEMBL24376600 | 0.84 | MLLT1 (0.65) | MLLT1MLLT3TSHRALDH1A1LMNA | |
| SCHEMBL29622187 | 0.78 | MLLT1 (0.78) | MLLT1MLLT3TSHRKMT2ARAB9A | |
| SCHEMBL24376454 | 0.78 | MLLT1 (0.78) | MLLT1MLLT3TSHRKMT2ARAB9A | |
| SCHEMBL24376394 | 0.76 | MLLT1 (0.71) | MLLT1MLLT3TSHRALDH1A1LMNA | |
| SCHEMBL13917047 | 0.74 | MLLT3 (0.65) | MLLT1MLLT3TSHRALDH1A1KMT2A | |
| SCHEMBL30704560 | 0.73 | MLLT3 (0.53) | MLLT1MLLT3 | |
| SCHEMBL30704721 | 0.73 | MLLT3 (0.53) | MLLT1MLLT3 | |
| SCHEMBL26911285 | 0.73 | MLLT3 (0.53) | MLLT1MLLT3 | |
| SCHEMBL24376942 | 0.71 | MLLT3 (0.43) | MLLT1MLLT3TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086937-A9 | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF ENL | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2022086937-A1 | HETEROBIFUNCTIONAL COMPOUNDS AS DEGRADERS OF ENL | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |