Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25154266 | 0.89 | TP53 (0.45) | TP53PKMALDH1A1MEN1KMT2A | |
| SCHEMBL356809 | 0.77 | TP53 (0.45) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL799217 | 0.77 | TP53 (0.45) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL799197 | 0.77 | TP53 (0.45) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL16473537 | 0.75 | TP53 (0.44) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL25154319 | 0.75 | TP53 (0.44) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL18081092 | 0.75 | TP53 (0.44) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL356808 | 0.75 | TP53 (0.44) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL16473467 | 0.75 | TP53 (0.44) | TP53ALDH1A1KDM4ERECQLLMNA | |
| SCHEMBL18080915 | 0.75 | TP53 (0.44) | TP53ALDH1A1KDM4ERECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086986-A1 | TREATMENT OF HEMATOLOGICAL MALIGNANCIES WITH INHIBITORS OF MENIN | KURA ONCOLOGY, INC. (US) | 2022-04-28 | — | — | WO | disclosed |