Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083904 | 1.00 | AR (0.46) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083783 | 1.00 | AR (0.46) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083934 | 0.91 | AR (0.48) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083865 | 0.91 | AR (0.47) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083813 | 0.90 | AR (0.47) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083786 | 0.90 | AR (0.47) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083774 | 0.89 | AR (0.46) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24083869 | 0.89 | KMT2A (0.55) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24377888 | 0.89 | KMT2A (0.55) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20556909 | 0.89 | KMT2A (0.52) | ARKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988541-A1 | HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2022-04-27 | — | — | EP | disclosed |