Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.47 |
| ▸ | AR | P10275 | 6/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.45 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546706 | 1.00 | CRBN (0.47) | CRBNARDDB1HPGDSHRH1 | |
| SCHEMBL29546787 | 1.00 | CRBN (0.47) | CRBNARDDB1HPGDSHRH1 | |
| SCHEMBL29547143 | 0.90 | CRBN (0.47) | CRBNARDDB1HPGDSHRH1 | |
| SCHEMBL24379304 | 0.90 | CRBN (0.47) | CRBNARDDB1HPGDSHRH1 | |
| SCHEMBL29547306 | 0.90 | CRBN (0.47) | CRBNARDDB1HPGDSHRH1 | |
| SCHEMBL24379104 | 0.84 | CRBN (0.54) | CRBNARDDB1HPGDS | |
| SCHEMBL29546958 | 0.84 | CRBN (0.54) | CRBNARDDB1HPGDS | |
| SCHEMBL22661510 | 0.83 | CRBN (0.42) | CRBNARDDB1IKZF2 | |
| SCHEMBL30249353 | 0.83 | CRBN (0.61) | CRBNARDDB1HPGDSCDK13 | |
| SCHEMBL23876486 | 0.82 | CRBN (0.46) | CRBNARDDB1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087125-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR PROTEIN | ARVINAS OPERATIONS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |