Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.70 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959012 | 0.91 | KCNH2 (0.74) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL22958975 | 0.91 | KCNH2 (0.74) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL13975809 | 0.91 | KCNH2 (0.74) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL15502364 | 0.90 | KCNH2 (0.87) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL22958978 | 0.89 | KCNH2 (0.65) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL24384693 | 0.83 | KCNH2 (0.85) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL15502385 | 0.83 | KCNH2 (0.85) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL24384584 | 0.83 | KCNH2 (0.85) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL15502428 | 0.82 | KCNH2 (1.00) | KCNH2TLR8TLR7CYP2D6 | |
| SCHEMBL19722983 | 0.82 | KCNH2 (1.00) | KCNH2TLR8TLR7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759083-B1 | 2,4-DIAMINOQUINAZOLINE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF VIRUS INFECTIONS, CANCER OR ALLERGIES | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2022-05-04 | — | — | EP | disclosed |