Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223467 | 0.82 | — | — | |
| SCHEMBL20936643 | 0.80 | CA1 (0.35) | CA1CA2CA4 | |
| SCHEMBL20457812 | 0.77 | CA1 (0.37) | CA1CA2CA4NOS1NOS2 | |
| SCHEMBL909980 | 0.76 | — | — | |
| SCHEMBL18828488 | 0.75 | — | — | |
| SCHEMBL910154 | 0.75 | — | — | |
| SCHEMBL12166485 | 0.74 | CA1 (0.43) | CA1CA2CA4NOS1NOS2 | |
| Hydrogen Sulfide SCHEMBL5678855 | 0.73 | — | — | |
| SCHEMBL27939665 | 0.71 | — | — | |
| SCHEMBL19864412 | 0.70 | CA1 (0.33) | CA1CA2CA4NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022094244-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2022-05-05 | — | — | WO | disclosed |