Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 13/20 | 0.45 |
| ▸ | BIRC3 | Q13489 | 11/20 | 0.45 |
| ▸ | TNF | P01375 | 5/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.39 |
| ▸ | BIRC7 | Q96CA5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12300019 | 1.00 | XIAP (0.45) | XIAPBIRC3TNFBIRC2BIRC7 | |
| SCHEMBL2438288 | 0.97 | XIAP (0.44) | XIAPBIRC3TNFBIRC2BIRC7 | |
| SCHEMBL12299863 | 0.97 | XIAP (0.44) | XIAPBIRC3TNFBIRC2BIRC7 | |
| SCHEMBL12299984 | 0.97 | XIAP (0.44) | XIAPBIRC3TNFBIRC2BIRC7 | |
| SCHEMBL2442320 | 0.95 | TNF (0.43) | XIAPBIRC3TNFBIRC2 | |
| SCHEMBL12299808 | 0.95 | TNF (0.43) | XIAPBIRC3TNFBIRC2 | |
| SCHEMBL2439386 | 0.95 | XIAP (0.42) | XIAPBIRC3TNFBIRC2 | |
| SCHEMBL2441783 | 0.95 | XIAP (0.42) | XIAPBIRC3TNFBIRC2 | |
| SCHEMBL12299817 | 0.95 | XIAP (0.42) | XIAPBIRC3TNFBIRC2 | |
| SCHEMBL12299813 | 0.95 | XIAP (0.42) | XIAPBIRC3TNFBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399683-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS (US) | 2013-03-19 | — | — | US | disclosed |
| US-20110237517-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237517-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | XIAP 1/4885BIRC3 5/4885TNF 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.