Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440400 | 0.85 | NR4A2 (0.53) | NR4A2CYP2C9KCNH2ACMSDEGLN1 | |
| SCHEMBL2436387 | 0.81 | NR4A2 (0.61) | NR4A2CYP2C9KCNH2ACMSDEGLN1 | |
| SCHEMBL1472422 | 0.79 | NR4A2 (0.83) | NR4A2CYP2C9KCNH2ALDH1A3ALDH1A1 | |
| SCHEMBL2088011 | 0.78 | NR4A2 (0.57) | NR4A2CYP2C9KCNH2ACMSDEGLN1 | |
| SCHEMBL3429998 | 0.77 | NR4A2 (0.73) | NR4A2CYP2C9KCNH2EGLN1ALDH1A3 | |
| SCHEMBL3774418 | 0.77 | CYP2C9 (0.56) | NR4A2CYP2C9KCNH2EGLN1ALDH1A1 | |
| SCHEMBL3368804 | 0.75 | NR4A2 (0.60) | NR4A2CYP2C9KCNH2EGLN1 | |
| SCHEMBL6521170 | 0.74 | NR4A2 (0.68) | NR4A2CYP2C9KCNH2ALDH1A3ALDH1A1 | |
| SCHEMBL1472658 | 0.74 | NR4A2 (0.80) | NR4A2CYP2C9KCNH2ALDH1A3ALDH1A1 | |
| SCHEMBL1472288 | 0.74 | NR4A2 (0.80) | NR4A2CYP2C9KCNH2ALDH1A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225241-B1 | Derivatives of N-phenyl-imidazo-(1,2-A)-pyridine-2-carboxamides, preparation thereof and therapeutic application thereof | SANOFI SA (FR) | 2011-09-14 | — | — | EP | claimed |