Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24398015 | 0.92 | BRD4 (0.48) | BRD4 | |
| SCHEMBL24397889 | 0.91 | BRD4 (0.47) | BRD4 | |
| SCHEMBL22588381 | 0.90 | BRD4 (0.52) | BRD4 | |
| SCHEMBL24397964 | 0.90 | BRD4 (0.48) | BRD4 | |
| SCHEMBL24397895 | 0.90 | BRD4 (0.47) | BRD4 | |
| SCHEMBL24397906 | 0.89 | BRD4 (0.49) | BRD4 | |
| SCHEMBL24397968 | 0.89 | BRD4 (0.47) | BRD4 | |
| SCHEMBL24398094 | 0.88 | BRD4 (0.48) | BRD4BRD2BRD3BRDT | |
| SCHEMBL24397849 | 0.86 | BRD4 (0.46) | BRD4EP300 | |
| SCHEMBL24397999 | 0.84 | BRD4 (0.48) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |