Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 16/20 | 0.60 |
| ▸ | RAF1 | P04049 | 10/20 | 0.60 |
| ▸ | CSF1R | P07333 | 8/20 | 0.60 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.60 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.60 |
| ▸ | ARAF | P10398 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638573 | 0.87 | BRAF (0.72) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399744 | 0.87 | BRAF (0.72) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638547 | 0.81 | BRAF (0.65) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399664 | 0.81 | BRAF (0.65) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399550 | 0.79 | BRAF (0.63) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399712 | 0.78 | BRAF (0.74) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL30401084 | 0.78 | BRAF (0.51) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399747 | 0.78 | BRAF (0.51) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399668 | 0.78 | BRAF (0.73) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638657 | 0.78 | BRAF (0.73) | BRAFRAF1CSF1RDDR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238967-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |