Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 14/20 | 0.47 |
| ▸ | RAF1 | P04049 | 10/20 | 0.47 |
| ▸ | CSF1R | P07333 | 5/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.47 |
| ▸ | ARAF | P10398 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375666 | 0.88 | BRAF (0.50) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638693 | 0.88 | BRAF (0.50) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399550 | 0.79 | BRAF (0.63) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399664 | 0.75 | BRAF (0.65) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638547 | 0.75 | BRAF (0.65) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL30400396 | 0.75 | BRAF (0.52) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL25372913 | 0.75 | BRAF (0.52) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL29638522 | 0.75 | BRAF (0.78) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399554 | 0.75 | BRAF (0.78) | BRAFRAF1CSF1RDDR1DDR2 | |
| SCHEMBL24399744 | 0.74 | BRAF (0.72) | BRAFRAF1CSF1RDDR1DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |