Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401274 | 0.87 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL24401101 | 0.80 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL29309838 | 0.79 | HDAC6 (0.51) | HDAC6HDAC1HDAC3HDAC2DDR1 | |
| SCHEMBL20535208 | 0.75 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL24401258 | 0.73 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL19389012 | 0.70 | SCN9A (0.64) | — | |
| SCHEMBL29309807 | 0.70 | HDAC6 (0.41) | HDAC6DDR1EPHX2 | |
| SCHEMBL29309818 | 0.68 | HDAC6 (0.39) | HDAC6EPHX2 | |
| SCHEMBL21743515 | 0.67 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC2 | |
| SCHEMBL29309802 | 0.67 | HDAC6 (0.50) | HDAC6HDAC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | HDAC1, HDAC6, HDAC11 | HDAC6 2/4885HDAC1 1/4885HDAC3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.