Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397663 | 0.89 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL3686993 | 0.88 | PPARA (0.56) | PPARAS1PR1S1PR2S1PR3ABCB11 | |
| SCHEMBL4575316 | 0.80 | PPARA (0.51) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL25299494 | 0.78 | PPARA (0.49) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14277886 | 0.78 | PPARA (0.54) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14399507 | 0.77 | EPHX1 (0.45) | PPARAPPARG | |
| SCHEMBL7094948 | 0.77 | PPARA (0.49) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL2440537 | 0.76 | PPARG (0.45) | PPARAPPARG | |
| SCHEMBL1586472 | 0.76 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL318984 | 0.75 | PPARG (0.68) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |