Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.38 |
| ▸ | KDM5A | P29375 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630798 | 1.00 | KCNJ1 (0.51) | KCNJ1HCAR2KDM5AKDM4CKDM5B | |
| SCHEMBL24409431 | 0.86 | KCNJ1 (0.50) | KCNJ1HCAR2KDM5AKDM4CKDM5B | |
| SCHEMBL24409254 | 0.79 | KCNJ1 (0.53) | KCNJ1ALDH1A1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL13954052 | 0.79 | HCAR2 (0.51) | HCAR2KDM5AKDM4CKDM5BKDM2B | |
| SCHEMBL13933900 | 0.78 | HCRTR1 (0.40) | HCAR2KDM5AKDM4CKDM5BKDM2B | |
| SCHEMBL24409340 | 0.77 | KCNJ1 (0.47) | KCNJ1ALDH1A1KDM4EGRIA1 | |
| SCHEMBL30567680 | 0.77 | KCNJ1 (0.47) | KCNJ1ALDH1A1KDM4EGRIA1 | |
| SCHEMBL16180341 | 0.76 | KCNJ1 (0.49) | KCNJ1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL20574271 | 0.76 | KCNJ1 (0.49) | KCNJ1HCAR2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL24409077 | 0.75 | KCNJ1 (0.48) | KCNJ1HCAR2ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144847-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | ELLIPSES PHARMA LTD (GB) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144847-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | NOTUM, FURIN, CYP4A11 | KCNJ1 2287/4885HCAR2 273/4885KDM5A 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.