Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630893 | 1.00 | KCNJ1 (0.49) | KCNJ1ALDH1A1L3MBTL1POLBCASP6 | |
| SCHEMBL20168079 | 0.81 | KCNJ1 (0.49) | KCNJ1ALDH1A1KDM4ECPB2CYP2A6 | |
| SCHEMBL30445326 | 0.81 | KCNJ1 (0.49) | KCNJ1ALDH1A1KDM4ECPB2CYP2A6 | |
| SCHEMBL23884612 | 0.81 | KCNJ1 (0.49) | KCNJ1ALDH1A1L3MBTL1POLBCASP6 | |
| SCHEMBL22606996 | 0.78 | KCNJ1 (0.60) | KCNJ1ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL20168007 | 0.77 | KCNJ1 (0.46) | KCNJ1ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL23884630 | 0.76 | KCNJ1 (0.44) | KCNJ1ALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL8191298 | 0.74 | KCNJ1 (0.51) | KCNJ1ALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL23501178 | 0.72 | KCNJ1 (0.54) | KCNJ1ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL1609848 | 0.72 | KCNJ1 (0.50) | KCNJ1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144847-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | ELLIPSES PHARMA LTD (GB) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144847-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | NOTUM, FURIN, CYP4A11 | KCNJ1 2287/4885ALDH1A1 644/4885L3MBTL1 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.