Allosamizoline

Allosamizoline

SCHEMBL2441099

CN(C)C1=N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)[C@@H]2O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OGA O60502 18/20 1.00
CHIA Q9BZP6 1/20 0.46
GAA P10253 1/20 0.35
HEXB P07686 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allosamizoline SCHEMBL12331251 1.00 OGA (1.00) OGACHIAGAAHEXB
Allosamizoline SCHEMBL691526 1.00 OGA (1.00) OGACHIAGAAHEXB
SCHEMBL2439536 0.86 OGA (0.75) OGACHIAGAAHEXB
SCHEMBL12331252 0.86 OGA (0.75) OGACHIAGAAHEXB
SCHEMBL12331389 0.84 OGA (0.72) OGACHIAGAAHEXB
SCHEMBL2439913 0.84 OGA (0.72) OGACHIAGAAHEXB
SCHEMBL12302368 0.74 OGA (0.58) OGAGAA
SCHEMBL2440207 0.74 OGA (0.58) OGAGAA
SCHEMBL12332281 0.74 OGA (0.58) OGAGAA
SCHEMBL2440567 0.73 OGA (0.58) OGACHIAGAAHEXB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079868-B2 Selective glycosidase inhibitors and uses thereof SIMON FRASER UNIVERSITY (CA) 2015-07-14 US disclosed
US-9079868-B2 Selective glycosidase inhibitors and uses thereof SIMON FRASER UNIVERSITY (CA) 2015-07-14 US disclosed
US-20110237631-A1 Selective Glycosidase Inhibitors and Uses Thereof SIMON FRASER UNIVERSITY (CA) 2011-09-29 US disclosed
US-20110237631-A1 Selective Glycosidase Inhibitors and Uses Thereof SIMON FRASER UNIVERSITY (CA) 2011-09-29 US disclosed
WO-2010012107-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2010-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237631-A1 Selective Glycosidase Inhibitors and Uses Thereof ENGASE, OGA, GALE OGA 2/4885CHIA 87/4885GAA 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.