Sugi Predict

Sugi Predict / Compounds / SCHEMBL24412467

SCHEMBL24412467

SCHEMBL24412467

CCCOCCCCOCCCCCOCC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ THRB P10828 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ TSHR P16473 2/20 0.42
▸ USP2 O75604 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ CES2 O00748 2/20 0.39
▸ SPHK2 Q9NRA0 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ EPHX2 P34913 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CES1 P23141 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ LPAR5 Q9H1C0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18902544 1.00 HTT (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL4482068 0.97 HTT (0.44) HTTMEN1THRBKMT2AMAPT
SCHEMBL3966692 0.95 HTT (0.56) HTTMEN1THRBKMT2AMAPT
SCHEMBL17137852 0.92 HTT (0.52) HTTMEN1THRBKMT2AMAPT
SCHEMBL874663 0.91 TSHR (0.43) HTTMEN1THRBKMT2AMAPT
SCHEMBL627684 0.91 TSHR (0.43) HTTMEN1THRBKMT2AMAPT
SCHEMBL28218907 0.91 HTT (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL760952 0.91 HTT (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL25996482 0.91 HTT (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL11759255 0.91 HTT (0.48) HTTMEN1THRBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022098990-A1 TARGETED CONJUGATES COMPRISING MODIFIED SIRNA ARBUTUS BIOPHARMA CORPORATION (CA) 2022-05-12 — — WO disclosed