Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 4/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 9/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.37 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | IL1B | P01584 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812657 | 0.81 | SRC (0.61) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20812163 | 0.77 | SRC (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22711508 | 0.75 | SRC (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22711376 | 0.75 | SRC (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20812154 | 0.74 | SRC (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20812342 | 0.74 | SRC (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22711433 | 0.74 | CRBN (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31068598 | 0.73 | BRD4 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22711390 | 0.73 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22711511 | 0.73 | CRBN (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | NEW YORK UNIVERSITY | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | MDM2, UBE3C, CUL1 | PSEN1 486/4885PSEN2 957/4885APH1B 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.