SCHEMBL24415243

SCHEMBL24415243

COCCc1nc2cnc3ccccc3c2n1CCCCNC1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.45
MAOB P27338 1/20 0.36
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24415034 0.88 TLR7 (0.39) TLR7MAOBHTR6
SCHEMBL1074029 0.88 TLR7 (0.42) TLR7MAOBHTR6
SCHEMBL30851335 0.84 TLR7 (0.65) TLR7
SCHEMBL20796977 0.84 TLR7 (0.65) TLR7
SCHEMBL14466065 0.81 TLR7 (0.62) TLR7
Hydrochloric Acid SCHEMBL4761666 0.81 TLR7 (0.61) TLR7
SCHEMBL24415342 0.80 TLR7 (0.41) TLR7
SCHEMBL24415020 0.80 TLR7 (0.43) TLR7
SCHEMBL20796917 0.80 SMN1; SMN2 (0.42) TLR7
SCHEMBL1949364 0.80 TLR7 (0.47) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220144822-A1 PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOQUINOLINE BioNTech SE (DE) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220144822-A1 PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOQUINOLINE TLR7, TLR3, TLR4 TLR7 1/4885MAOB 2269/4885HTR6 811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.