SCHEMBL2441572

SCHEMBL2441572

CCCCCCCCN(Cc1cccc(OC(C)(C)C(=O)O)c1)c1nc2ccccc2o1

nearest known ligand 0.82

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.82
PPARG P37231 16/20 0.82
PPARD Q03181 15/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6544215 1.00 PPARA (0.82) PPARAPPARGPPARD
SCHEMBL6543654 1.00 PPARA (0.82) PPARAPPARGPPARD
SCHEMBL6544087 0.99 PPARA (0.83) PPARAPPARGPPARD
SCHEMBL6542938 0.96 PPARA (0.85) PPARAPPARGPPARD
SCHEMBL6542936 0.94 PPARA (0.83) PPARAPPARGPPARD
SCHEMBL6543441 0.92 PPARA (0.81) PPARAPPARGPPARD
SCHEMBL6542922 0.92 PPARA (0.81) PPARAPPARGPPARD
SCHEMBL6543068 0.92 PPARA (0.82) PPARAPPARGPPARD
SCHEMBL6543469 0.92 PPARA (0.82) PPARAPPARGPPARD
SCHEMBL6543120 0.92 PPARA (0.81) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP claimed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US claimed
EP-1433786-B1 Benzoxazole compound and pharmaceutical composition containing the compound KOWA CO (JP) 2011-09-21 EP disclosed
EP-1433786-B1 Benzoxazole compound and pharmaceutical composition containing the compound KOWA CO (JP) 2011-09-21 EP disclosed
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP disclosed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US disclosed