Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441664 | 1.00 | SRD5A2 (0.47) | SRD5A2MEN1KMT2AHSP90AA1NPC1 | |
| SCHEMBL2018949 | 0.94 | SRD5A2 (0.46) | SRD5A2MEN1KMT2AHSP90AA1NPC1 | |
| SCHEMBL2018948 | 0.94 | SRD5A2 (0.46) | SRD5A2MEN1KMT2AHSP90AA1NPC1 | |
| SCHEMBL2016768 | 0.88 | SRD5A2 (0.50) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16918467 | 0.88 | SRD5A2 (0.50) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2016771 | 0.88 | SRD5A2 (0.50) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2021474 | 0.88 | SRD5A2 (0.49) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2447542 | 0.88 | SRD5A2 (0.49) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2447541 | 0.88 | SRD5A2 (0.49) | SRD5A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14327889 | 0.82 | MEN1 (0.51) | SRD5A2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542554-A1 | PROCESSES FOR THE PREPARATION OF S1P1 RECEPTOR MODULATORS AND CRYSTALLINE FORMS THEREOF | Arena Pharmaceuticals, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109471-A1 | PROCESSES FOR THE PREPARATION OF S1P1 RECEPTOR MODULATORS AND CRYSTALLINE FORMS THEREOF | ARENA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |