SCHEMBL24417285

SCHEMBL24417285

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4-n4c5ccccc5c5ccc6oc7c(-c8cccc(-c9ccccc9)c8)cccc7c6c54)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 8/20 0.35
ALOX5 P09917 1/20 0.34
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
PIK3CD O00329 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
PIK3CG P48736 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24417240 0.97 PRKDC (0.32) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL24417237 0.96 PRKDC (0.33) PRKDCPIM1CSNK2A2CSNK2BPIM3
SCHEMBL24417238 0.95 PRKDC (0.33) PRKDCALOX5PIK3CDPIK3CAPIK3CB
SCHEMBL24417284 0.95 PRKDC (0.33) PRKDCALOX5PIK3CDPIK3CAPIK3CB
SCHEMBL24417236 0.95 PRKDC (0.33) PRKDCALOX5PIK3CDPIK3CAPIK3CB
SCHEMBL24417239 0.94 PRKDC (0.32) PRKDCPIM1CSNK2A2CSNK2BPIM3
SCHEMBL24417323 0.91 PRKDC (0.31) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL24417322 0.90 PRKDC (0.38) PRKDCALOX5PIK3CDPIK3CAPIK3CB
SCHEMBL27445392 0.89 PIM1 (0.32) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL27445389 0.89 PIM1 (0.32) PRKDCALOX5PIM1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220149289-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-05-12 US disclosed