Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.48 |
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.33 |
| ▸ | MARS1 | P56192 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24606263 | 1.00 | TMPRSS2 (0.48) | TMPRSS2POLRMTRIPK1MARS1 | |
| SCHEMBL24606264 | 1.00 | TMPRSS2 (0.48) | TMPRSS2POLRMTRIPK1MARS1 | |
| Obeldesivir SCHEMBL27216326 | 0.94 | TMPRSS2 (0.49) | TMPRSS2POLRMTRIPK1 | |
| Obeldesivir SCHEMBL23959875 | 0.94 | TMPRSS2 (0.49) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL23959956 | 0.93 | TMPRSS2 (0.47) | TMPRSS2POLRMTRIPK1MARS1 | |
| SCHEMBL24312544 | 0.93 | TMPRSS2 (0.47) | TMPRSS2POLRMTRIPK1MARS1 | |
| SCHEMBL25821935 | 0.92 | TMPRSS2 (0.48) | TMPRSS2POLRMTRIPK1 | |
| SCHEMBL24606265 | 0.91 | TMPRSS2 (0.45) | TMPRSS2RIPK1 | |
| SCHEMBL24917639 | 0.91 | TMPRSS2 (0.46) | TMPRSS2POLRMTRIPK1MARS1 | |
| SCHEMBL25910137 | 0.91 | TMPRSS2 (0.46) | TMPRSS2POLRMTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098371-A1 | PRODRUGS OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGUES FOR ANTIVIRAL TREATMENT | YAN MATTHEW (US) | 2022-05-12 | — | — | WO | disclosed |