Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25764429 | 1.00 | TYMP (0.47) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL26781724 | 1.00 | TYMP (0.47) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL25762390 | 0.93 | TYMP (0.50) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL24052110 | 0.93 | TYMP (0.50) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL12173904 | 0.88 | TYMP (0.46) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL25764456 | 0.87 | SMN1; SMN2 (0.39) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL24268463 | 0.84 | SMN1; SMN2 (0.39) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL22525162 | 0.84 | SMN1; SMN2 (0.39) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL23813663 | 0.83 | TYMP (0.39) | TYMPSMN1; SMN2ALDH1A1LMNAALB | |
| SCHEMBL13846304 | 0.83 | TYMP (0.39) | TYMPSMN1; SMN2ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |