Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24420546 | 0.90 | FGFR1 (0.48) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL24420685 | 0.90 | FGFR1 (0.48) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL25611142 | 0.88 | FGFR1 (0.42) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL27053994 | 0.86 | FGFR1 (0.40) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL16513183 | 0.85 | FGFR1 (0.37) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL15482195 | 0.85 | FGFR1 (0.37) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL29332978 | 0.84 | FGFR1 (0.41) | FGFR1SLC22A6POLBHSD17B10 | |
| SCHEMBL15501180 | 0.83 | FGFR1 (0.41) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL23584293 | 0.83 | FGFR1 (0.44) | FGFR1SLC22A6PDE3APDE4DSLC29A1 | |
| SCHEMBL17384630 | 0.83 | FGFR1 (0.39) | FGFR1SLC22A6PDE3APDE4DSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |