SCHEMBL24420899

SCHEMBL24420899

CCC(=O)C(CCCNC(N)=O)NC(=O)[C@@H](NC(C)C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 10/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ C3AR1 Q16581 1/20 0.33
▸ PRSS1 P07477 2/20 0.33
▸ SIRT6 Q8N6T7 1/20 0.32
▸ SIRT1 Q96EB6 1/20 0.32
▸ LMNA P02545 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ REN P00797 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23220183 1.00 FURIN (0.33) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL19198733 1.00 FURIN (0.33) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL21503852 0.91 EPHX1 (0.33) SMN1; SMN2C3AR1SIRT6SIRT1
SCHEMBL21503883 0.90 NPY4R (0.38) FURINSMN1; SMN2
SCHEMBL19678198 0.88 FURIN (0.36) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL18661754 0.88 SMN1; SMN2 (0.34) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL18661790 0.88 SMN1; SMN2 (0.34) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL26499160 0.88 SMN1; SMN2 (0.34) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL17448412 0.88 SMN1; SMN2 (0.34) FURINSMN1; SMN2C3AR1PRSS1SIRT6
SCHEMBL23079360 0.87 FURIN (0.39) FURINSMN1; SMN2C3AR1PRSS1SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220143038-A1 LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF PURETECH LYT, INC. (US) 2022-05-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143038-A1 LIPID PRODRUGS OF MYCOPHENOLIC ACID AND USES THEREOF MALT1, CYP2B6, LIPA FURIN 2029/4885SMN1; SMN2 4037/4885C3AR1 575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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