Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 17/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24422906 | 1.00 | MEN1 (0.46) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL24422907 | 1.00 | MEN1 (0.46) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL29586159 | 0.97 | MEN1 (0.48) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL24423548 | 0.92 | KDM5A (0.51) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL25090685 | 0.90 | MEN1 (0.43) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL29586247 | 0.90 | MEN1 (0.43) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL29243680 | 0.90 | MEN1 (0.43) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL25090686 | 0.90 | MEN1 (0.43) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL25090684 | 0.90 | MEN1 (0.43) | MEN1ALDH1A1KMT2AKDM5AKDM5B | |
| SCHEMBL29585501 | 0.90 | SMO (0.46) | MEN1ALDH1A1KMT2AKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | claimed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | claimed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | claimed |
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |