Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423323 | 0.77 | BTK (0.39) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL360739 | 0.75 | BTK (0.50) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL24424562 | 0.75 | BTK (0.47) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL24423246 | 0.74 | BTK (0.43) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL18929028 | 0.74 | BTK (0.51) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL13035982 | 0.74 | BTK (0.51) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL18535099 | 0.73 | BTK (0.42) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL21724861 | 0.73 | BTK (0.46) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL28535097 | 0.73 | BTK (0.46) | BTKCTSKGAAKDM1AMAOB | |
| SCHEMBL20617600 | 0.73 | BTK (0.48) | BTKCTSKGAAKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |