Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24422979 | 1.00 | POLB (0.44) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL24422978 | 1.00 | POLB (0.44) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL24424330 | 1.00 | POLB (0.44) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL24422977 | 1.00 | POLB (0.44) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL25090687 | 1.00 | POLB (0.44) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL24423853 | 1.00 | POLB (0.44) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL25090883 | 0.93 | POLB (0.43) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL25090882 | 0.93 | POLB (0.43) | POLBCCNT1CDK9KMT2AROCK2 | |
| SCHEMBL24423977 | 0.91 | POLB (0.42) | POLBCCNT1CDK9KMT2AMAPT | |
| SCHEMBL29585038 | 0.91 | POLB (0.42) | POLBCCNT1CDK9KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |