Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29584737 | 1.00 | CHEK1 (0.33) | CHEK1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL25090908 | 0.95 | CHEK1 (0.33) | CHEK1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL24424426 | 0.94 | CHEK1 (0.33) | CHEK1FFAR4TLR9TLR8TLR7 | |
| SCHEMBL29583183 | 0.93 | CHEK1 (0.33) | CHEK1FFAR4TBK1KDM5AEGLN1 | |
| SCHEMBL29583159 | 0.93 | CHEK1 (0.35) | CHEK1FFAR4TBK1KDM5AKCNH2 | |
| SCHEMBL24424325 | 0.93 | CHEK1 (0.33) | CHEK1FFAR4TBK1KDM5AEGLN1 | |
| SCHEMBL25090941 | 0.93 | CHEK1 (0.35) | CHEK1FFAR4TBK1KDM5AKCNH2 | |
| SCHEMBL29583623 | 0.91 | EPHX2 (0.32) | CHEK1FFAR4TBK1KDM5A | |
| SCHEMBL24424280 | 0.91 | EPHX2 (0.32) | CHEK1FFAR4TBK1KDM5A | |
| SCHEMBL24423280 | 0.91 | CHEK1 (0.32) | CHEK1FFAR4TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |