SCHEMBL2442525

SCHEMBL2442525

CCCc1cc(C2(c3ccc(Oc4ccc(N)cc4C(C)C)c(CCC)c3)c3ccccc3-c3ccccc32)ccc1Oc1ccc(N)cc1C(C)C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
OPRK1 P41145 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
MAOA P21397 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446771 0.96 KDM4E (0.42) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2441823 0.91 SMN1; SMN2 (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2444659 0.90 KDM4E (0.38) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2441683 0.90 KDM4E (0.49) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2440276 0.89 SMN1; SMN2 (0.50) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446794 0.87 SMN1; SMN2 (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2443557 0.86 MEN1 (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2441121 0.86 MEN1 (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL3885665 0.86 KDM4E (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL29418399 0.85 KDM4E (0.44) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed